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. 2016 Sep 8;12(5):3273–3277. doi: 10.3892/ol.2016.5105

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Copyright: © Angelini et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Immunohistochemical detection of permeability glycoprotein expression in cytocentrifuged microparticles from human plasma (magnification, ×40). (A) There were few MPs in the plasma from healthy patients, and those MPs were negative for Pgp expression. (B) Numerous, clustered MPs were detected in the plasma samples from 30 cancer patients without TF activity, although these MPs showed very low expression of Pgp. (C) Numerous, clustered MPs were detected in the plasma samples from 20 cancer patients with elevated TF activity, and these MPs showed a high expression of Pgp, as indicated by the intense brown colouration. Black arrows indicate MPs and clusters of MPs. Pgp, permeability glycoprotein; MPs, micrcoparticles; TF, tissue factor.