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. 2016 Aug 24;12(5):3278–3284. doi: 10.3892/ol.2016.5042

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Copyright: © Shen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — c(RGDfV) exhibits effects on leukemia cell apoptotic rates. (A) Original flow cytometry data. (B) Quantification showed that the percentage of apoptotic MV4–11 cells was lower in the presence of osteoblasts, which can enhance the drug resistance and antiapoptotic effect of leukemia cells. Osteoblasts also partially prevented Ara-C-induced apoptosis in the MV4–11 cells: following treatment with 0.2 µg/ml Ara-C, a high percentage of apoptosis occurred, while the apoptosis rate was lower in leukemia cells in the presence of bone marrow stromal cells. Ara-C, cytarabine; PBS, phophate-buffered saline; R, c(RGDfV). *P<0.05.