Figure 5.

Overexpression of miR-138 suppressed tumor growth in HeLa xenografts. (A) Morphological characteristics of tumors in mice inoculated with HeLa/miR-138 or HeLa/miR-NC are shown. (B) Growth curves of tumor volumes in xenografts of nude mice. (C) Weight of tumor tissues was measured in each group. (D) hTERT was determined by western blot analysis. β-actin was used as an internal control. **P<0.01 vs. miR-NC group. miR-138, microRNA-138; miR-NC, miR-negative control; hTERT, human telomerase reverse transcriptase.