Table II.
Group | Proliferation inhibition rate (%) | Apoptosis rate (%) | XIAP expression (FI) |
---|---|---|---|
Control | 7.60±6.22 | 7.80±0.85 | 0.90±0.57 |
Cisplatin | 29.83±1.60a | 22.33±0.97a | 0.36±0.04a |
Mat | |||
0.5 g/l | 15.93±2.50a | 12.63±0.85a | 0.67±0.06a |
1.0 g/l | 23.20±2.33a, b | 16.93±0.81a, b | 0.50±0.03a, b |
1.5 g/l | 36.73±2.48a, b | 27.63±0.70a, b | 0.28±0.04a, b |
Mat + cisplatin | |||
0.5 g/l | 46.00±1.45a, c | 36.47±3.00a, c | 0.21±0.02a, c |
1.0 g/l | 56.27±2.24a,c,d | 44.03±2.06a,c,d | 0.14±0.02a,c,d |
1.5 g/l | 68.83±1.35a,c,d | 69.00±5.48a,c,d | 0.07±0.03a,c,d |
F-value | 141.581 | 203.905 | 162.600 |
P-value | 0.01 | <0.0001 | <0.0001 |
Comparison with the control group;
comparison with the 0.5 g/l Mat group;
comparison with 0.5 g/l Mat combined with the cisplatin group; P<0.05.
Comparison between the Mat group and Mat combined with cisplatin at different concentrations were statically significant (P<0.05). Mat, matrine; XIAP, X-linked inhibitor of apoptosis protein.