Table II.
Univariable cox regression analysis on overall survival.
| Parameter | Hazard ratio | 95% confidence interval | P-value |
|---|---|---|---|
| Periostin (high) | 1.80 | 0.99–3.27 | 0.050 |
| α-SMA (high) | 1.03 | 0.56–1.88 | 0.930 |
| CD31 (high) | 1.03 | 0.57–1.88 | 0.923 |
| Collagen (high) | 1.26 | 0.69–2.31 | 0.441 |
| ASI (high) | 1.12 | 0.62–2.04 | 0.706 |
| Nodal status | 0.001a | ||
| N1/N0 | 2.27 | 1.10–4.67 | 0.026 |
| N2–3/N0 | 4.05 | 1.96–8.37 | <0.001 |
| Grade | 0.823a | ||
| G2/G3 | 0.82 | 0.44–1.54 | 0.533 |
| Tumor status | 0.222a | ||
| T2/T1 | 1.47 | 0.69–3.16 | 0.321 |
| T3/T1 | 2.06 | 0.73–5.79 | 0.171 |
| T4/T1 | 3.64 | 0.97–13.6 | 0.055 |
ASI, activated stroma index (1);
a
likelihood ratio test for overall effect.