Figure 3.

ROC curves were used to determine the cutoff for the IRS of PARP-1 expression based on the (A) lymph node metastasis status, (B) lymphatic invasion status, (C) distant metastasis status, (D) OS status and (E) DFS status of breast cancer patients. The sensitivity and specificity for each outcome were plotted and the AUCs and P-values were indicated. PARP-1, poly (adenosine diphosphate-ribose) polymerase 1; ROC, receiver operating characteristic; IRS, immunoreactivity score; AUCs, areas under curve.