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. 2016 Sep 22;12(5):3825–3835. doi: 10.3892/ol.2016.5169

Figure 7.

Figure 7.

Analysis of the prognostic significance of PARP-1 in specific subgroups of breast cancer patients with various TNM stages. Survival rate curves show that high PARP-1 expression levels were significantly associated with shorter (A) OS or (B) DFS in patients with advanced TNM stage (III–IV) but not (C and D) early TNM stage (I–II). A log-rank test was performed to evaluate the statistical significance. Asterisks (*) indicated statistical significance. PARP-1, poly (adenosine diphosphate-ribose) polymerase 1; OS, overall survival; DFS, disease-free survival; TNM, tumor-node-metastasis.