Table II.

Association of the expression of PARP-1 with clinicopathological features of gastric cancer.

	High expression
Features	n	%	P-valuea
Age at diagnosis (years)			0.105
≤60	130	43.9
>60	136	50.7
Gender			0.575
Male	194	47.9
Female	72	45.3
Tumor location			0.057
Lower	111	43.2
Middle	104	52.3
Upper	15	35.7
Tumor size (cm)			0.123
≤5.0	108	45.0
>5.0	146	51.8
Histologic differentiation			<0.001b
High	18	22.2
Moderate	53	44.5
Low	190	53.5
Invasion depth			0.037b
T1	20	35.1
T2	36	42.9
T3	163	48.1
T4	31	63.3
H. pylori			0.032b
Negative	38	42.7
Positive	117	56.2
Ascites			0.253
Negative	142	46.9
Positive	73	41.5
Lymphatic invasion			<0.001b
Negative	136	40.4
Positive	118	58.1
Lymph node metastasis			<0.001b
Negative	84	35.4
Positive	180	57.0
Distant metastasis			0.263
Negative	123	43.0
Positive	72	48.6
TNM stage			0.015b
I~II	76	40.9
III~IV	154	52.2

^aP-value obtained from pearson chi-square or Fisher's exact test

^bstatistically significant (P<0.05); H. pylori, Helicobacter pylori; TNM, tumor-node-metastasis; PARP-1, poly (adenosine diphosphate-ribose) polymerase 1.