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. 2016 Sep 29;12(5):3836–3844. doi: 10.3892/ol.2016.5207

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Immunohistochemistry of mouse xenografts from human lung adenocarcinoma A459 cells transfected with si10 and pU6 (magnification, ×100). (A) Intensity of COX-2 expression staining was scored in the xenografts as follows: A549, 1; A549-pU6s, 1; A549-si10, 0. (B) Intensity of matrix metalloproteinase-2 expression staining was scored in the xenografts as follows: A549, 3; A549-pU6, 3; A549-si10, 1. (C) Intensity of vascular endothelial growth factor expression staining was scored in the xenografts as follows: A549, 2; A549-pU6, 2; A549-si10, 1. Scale bar, 200 µm. COX-2, cyclooxygenase-2; si10, small interfering RNA against COX-2.