Table IV.
TP53 mutations identified in PDAC patients.
| Sample ID | Mutation | Protein change | Type | transFIC prediction |
|---|---|---|---|---|
| 1 | g.chr17:7578553 | p.T126S | SNP | Driver mutation |
| 2 | g.chr17:7577141 | p.G266V | SNP | Driver mutation |
| 3 | g.chr17:7577120 | p.R273C | SNP | Driver mutation |
| 4 | g.chr17:7578406 | p.A175H | SNP | Driver mutation |
| 5 | g.chr17:7577547 | p.G245N | SNP | Driver mutation |
| 6 | g.chr17:7579388 | p.G1100Ter | SNP | Strongly affecting mutation |
| 7 | g.chr17:7577553 | p.C242S | SNP | Strongly affecting mutation |
| 7 | g.chr17:7578434 | p.S166A | SNP | Strongly affecting mutation |
| 8 | g.chr17:7577570 | p.M237I | SNP | Driver mutation |
| 10 | g.chr17:7577103 | p.R280fs | INDEL | Putative affecting |
| 17 | g.chr17:7577559 | p.S241F | SNP | Driver mutation |
| 24 | g.chr17:7578448 | p.A161N | SNP | Strongly affecting mutation |
| 25 | g.chr17:7578201 | p.H214A | SNP | Strongly affecting mutation |
PDAC, pancreatic ductal adenocarcinoma; SNP, single nucleotide polymorphisms; INDEL, small insertions and deletions; transFIC, TRANSformed functional impact for cancer.