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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Neuroimaging Clin N Am. 2016 Sep 2;26(4):601–620. doi: 10.1016/j.nic.2016.06.008

Figure 7.

Figure 7

Diffuse leptomeningeal spread of metastatic disease. 47-year old woman with known systemic spread of metastatic breast cancer presented for follow-up MR imaging. Diffuse leptomeningeal spread of disease is noted to involve multiple cranial nerves (curved arrows) including right trigeminal nerve as it courses through Meckle’s Cave (bottom left) and the right oculomotor nerve (bottom right). FLAIR imaging can be helpful in delineating subtle leptomeningeal metastatic diesae (top left). FLAIR hyperintensity within multiple sulci (arrows) is nonspecific but in this patient suggests sites of disease burden. The right tentorium also demonstrates FLAIR hyperintensity and enhancement (top right; arrow head) suggesting metastatic focus.