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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Neuroimaging Clin N Am. 2016 Sep 2;26(4):601–620. doi: 10.1016/j.nic.2016.06.008

Table 2.

Aging of Blood Products on MR Imaging

Stage Time Hemoglobin State T1 Signal Intensity T2 Signal Intensity
Hyperacute Less than 24 hours Intracellular Oxyhemoglobin Isointense Hyperintense
Acute Less than 48 hours Intracellular Deoxyhemoglobin Isointense Hypointense
Early Subactue 2–14 days Intracellular Methemoglobin Hyperintense Hypointense
Late Subacute 10–21 days Extracellular Methaemoglobin Hyperintense Hyperintense
Chronic Greater than 21 days Hemosiderin Hypointense Hypointense

Note: Complied from data presented by Chalela, Aygun, and Bradley.