Table IV.
Rank order of efficacy by IC50 of Chinese nutritional herbs on the estrogen receptor functional phenotype.
| Herbal extract | IC50 (%)a |
|---|---|
| LBB | 0.001 |
| CO | 0.070 |
| EU | 0.090 |
| DA | 0.130 |
| PC | 0.260 |
| LL | 0.280 |
| LBF | 0.390 |
| EG | 0.440 |
| CS | 0.570 |
| LC | 0.620 |
| AS | 1.170 |
a
Determined after a 7-day treatment with the herbal extract. Estrogen receptor functional MCF-7 cells were maintained in culture medium supplemented with 0.7% serum and 20 nM 17β-estradiol. IC, inhibitory concentration. AS, Angelica sinensis; CO, Cornus officinalis; CS, Cuscuta sinensis; DA, Dipsacus asperoides; EG, Epimedium grandiflorum; EU, Eucommia ulmoides; LC, Ligusticum chuanxiong; LL, Ligustium lucidum; LBB, Lycium barbarum bark; LBF, Lycium barbarum fruit; PC, Psoralea corylifolia.