Table VI.
Effects of extracts from LBB, EG and CO on the cell cycle progression of the estrogen receptor non-functional phenotype.
Cell cycle-phase population (%)a | ||||
---|---|---|---|---|
Treatment | Concentration | G1 | S | G2/M |
E2 | 20 nM | 50.1±5.8 | 34.2±3.9 | 14.9±1.6 |
LBB | 0.05% | 42.2±4.9 | 17.7±1.9c | 38.1±1.8d |
EG | 0.80% | 77.7±7.8b | 19.8±1.9c | 2.4±0.2e |
CO | 0.10% | 66.9±6.7b | 18.5±1.8c | 14.6±1.4 |
Determined by flow cytometry after a 48-h. treatment. Data are represented as the mean ± SD (n=3/treatment group).
P=0.04 vs. E2
P=0.04 vs. E2
P=0.01 vs. E2
P=0.02 vs. E2. E2, 17β-estradiol; LBB, Lycium barbarum bark; EG, Epimedium grandiflorum; CO, Cornus officinalis.