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. 2016 Sep 21;12(5):4173–4180. doi: 10.3892/ol.2016.5163

Figure 5.

Figure 5.

Effect of miR-21 on the apoptosis of Jurkat cells. Flow cytometry analysis of (A) Jurkat cells, (B) adv-miR-21-control, (C) adv-miR-21, (D) adv-anti-miR-21-control, and (E) adv-anti-miR-21. (F) The apoptosis rate of Jurkat cells increased in cells infected with adv-miR-21-control and adv-anti-miR-21-control compared with non infected Jurkat cells (*P<0.05). The apoptosis rate of the adv-miR-21 group was significantly inhibited compared with the adv-miR-21-control (**P<0.01) and the adv-anti-miR-21-control groups, indicating that downregulating miR-21 in Jurkat cells significantly increased apoptosis (**P<0.01). miR-21, microRNA 21; adv, adenovirus; PE, phycoerythrin; 7-AAD, 7-aminoactinomycin D.