Table 4.
Ultrasound Measurement |
Short Palpebral Fissure Lengthb |
p | Smooth Philtrumc | p | Thin Vermiliond | p | FASDe | p | Delayed Neurobehavioral Development |
p | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Present N=12 |
Absent N=84 |
Present N=14 |
Absent N=84 |
Present N=27 |
Absent N=71 |
Present N=15 |
Absent N=83 |
Present N=48 |
Absent N=42 |
||||||
TCD | 20.2±0.4 | 20.6±0.1 | 0.230 | 20.6±0.3 | 20.6±0.1 | 0.871 | 20.5±0.2 | 20.6±0.1 | 0.735 | 20.1±0.3 | 20.7±0.1 | 0.089 | 20.5±0.2 | 20.8±0.2 | 0.337 |
OFD | 61.6±2.3 | 62.5±0.9 | 0.724 | 68.7±2.0 | 61.5±0.8 | 0.002 | 64.8±1.4 | 61.7±0.9 | 0.079 | 61.3±2.0 | 62.7±0.8 | 0.504 | 61.5±1.2 | 64.1±1.2 | 0.131 |
CCD | 25.0±0.8 | 23.9±0.3 | 0.168 | 23.9±0.8 | 24.0±0.3 | 0.859 | 23.9±0.6 | 24.0±0.4 | 0.825 | 24.9±0.7 | 23.8±0.3 | 0.208 | 24.2±0.4 | 23.9±0.4 | 0.564 |
FTD | 37.0±1.2 | 38.3±0.4 | 0.294 | 38.5±1.2 | 38.1±0.5 | 0.769 | 38.1±0.8 | 38.2±0.5 | 0.898 | 36.8±1.1 | 38.5±0.5 | 0.176 | 37.5±0.6 | 39.5±0.6 | 0.023 |
OOD | 32.8±0.5 | 32.5±0.2 | 0.626 | 33.1±0.5 | 32.5±0.2 | 0.204 | 33.0±0.3 | 32.4±0.2 | 0.144 | 32.8±0.5 | 32.5±0.2 | 0.606 | 32.6±0.3 | 32.6±0.3 | 0.989 |
IOD | 10.48±0.62 | 9.47±0.24 | 0.136 | 9.76±0.59 | 9.56±0.24 | 0.754 | 9.91±0.41 | 9.46±0.26 | 0.362 | 10.88±0.54 | 9.35±0.23 | 0.010 | 10.24±0.30 | 8.98±0.33 | 0.006 |
OD | 10.46±0.43 | 9.66±0.16 | 0.085 | 9.82±0.41 | 9.75±0.17 | 0.878 | 10.25±0.28 | 9.56±0.18 | 0.039 | 10.24±0.38 | 9.67±0.17 | 0.171 | 9.57±0.22 | 10.11±0.24 | 0.095 |
FTD/OD | 3.59±0.22 | 4.04±0.09 | 0.060 | 3.96±0.22 | 4.00±0.09 | 0.881 | 3.79±0.15 | 4.07±0.10 | 0.122 | 3.64±0.21 | 4.06±0.09 | 0.070 | 3.99±0.11 | 3.96±0.13 | 0.841 |
OFD/IOD | 6.12±0.50 | 6.93±0.19 | 0.136 | 7.39±0.46 | 6.74±0.19 | 0.202 | 6.87±0.33 | 6.83±0.21 | 0.916 | 5.85±0.43 | 7.03±0.18 | 0.013 | 6.34±0.24 | 7.37±0.26 | 0.005 |
FTD/IOD | 3.71±0.34 | 4.27±0.13 | 0.131 | 4.16±0.33 | 4.21±0.13 | 0.871 | 4.07±0.23 | 4.26±0.15 | 0.484 | 3.55±0.30 | 4.33±0.13 | 0.020 | 3.91±0.17 | 4.54±0.19 | 0.013 |
Estimated marginal means +/− SE; adjusted for gestational age at ultrasound and maternal smoking
≤10th percentile
4 or 5 on Lipometer scale
4 or 5 on Vermilion Border Lipometer scale
Fetal Alcohol Spectrum Disorder