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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Prenat Diagn. 2016 Jul 25;36(9):812–822. doi: 10.1002/pd.4862

Figure 2.

Figure 2

PCA analyses highlighted dysregulation of genes encoded on the nontrisomic chromosomes. (A–C) The genes expressed from the non trisomic chromosomes (non-HSA) separated each aneuploid condition (red) from the euploid samples (blue), suggesting genome-wide effects. (D–F) A categorical PCA revealed the involvement of gene dysregulation on specific non trisomic chromosomes for each syndrome and overlapping patterns. In all cases, the duplicated chromosome was highlighted. Expression of genes on the Y-chromosome identified pregnancies in which the fetus was male. * denotes p ≤ 0.05 as determined by FactoMineR.