Table 4. DE hub genes in the Sox6 KO heart.
Gene | Cluster | Fold change in Sox6 KO | Known/potential function in the heart |
---|---|---|---|
Tubb2b | N2 | 1.9 (P7) | Unknown |
Egr1 | J4 | 0.4 (P7), 0.3 (P14) | Angiogenesis, hypertrophy, cardioprotection |
Hspb8 | A1 | 0.6 (P30) | activator of nuclear and mitochondrial functions of STAT3 |
Il15 | A3 | 0.6 (P7) | Protection from oxidative stress |
Lyz1 | A4 | 0.7 (P7), 0.6 (P30) | innate immune response |
Klf9 | A6 | 2.5 (P1) | Unknown |