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. 2016 Nov 10;11(11):e0166449. doi: 10.1371/journal.pone.0166449

Table 2. Univariable and multivariable analysis of variables in relation to Hazard Ratio (HR) of pancreatic cancer patients in the Netherlands, period 1989–2011 (n = 34,757).

Variables Univariable Multivariable
% HR 95% CI HR 95% CI
SES Low 30 1 Reference 1 Reference
Medium 40 0.96 094–0.99 0.96 0.94–0.99
High 30 0.92 0.90–0.95 0.93 0.90–0.95
Age 70(median) 1.0 1.0–1.0 1.02 1.01–1.02
Gender Men 49 1 Reference 1 Reference
Women 51 0.99 0.98–1.02 0.96 0.94–0.98
Localization Head 68 1 Reference 1 Reference
Non-head 19 1.3 1.2–1.3 1.1 1.07–1.13
NOS/Overlapping lesion 13 1.5 1.4–1.5 1.20 1.16–1.24
Differentiation Well 3 1 Reference 1 Reference
Moderate 11 1.1 1.1–1.2 1. 1.13–1.30
Poor 11 1.7 1.6–1.8 1.5 1.43–1.64
Undifferentiated 1 2.9 2.5–3.4 1.95 1.69–2.25
Unknown 75 1.9 1.8–2.0 1.21 1.43–1.29
Stage local 14 1 Reference 1 Reference
Beyond pancreas 28 1.0 0.9–1.0 1203 1.15–1.24
metastatic 45 2.4 2.3–2.5 2.29 2.21–2.37
unknown 5 1.5 1.5–1.6 1.31 1.26–1.37
Resection No 90 1 Reference 1 Reference
Yes 10 0.3 0.3–0.3 0.43 0.41–0.45
Adjuvant chemotherapy No 80 1 Reference Not included in multivariable analysis
Yes 20 0.3 0.3–0.3

CI: Confidence Interval.