Table 2. Univariable and multivariable analysis of variables in relation to Hazard Ratio (HR) of pancreatic cancer patients in the Netherlands, period 1989–2011 (n = 34,757).
Variables | Univariable | Multivariable | ||||
---|---|---|---|---|---|---|
% | HR | 95% CI | HR | 95% CI | ||
SES | Low | 30 | 1 | Reference | 1 | Reference |
Medium | 40 | 0.96 | 094–0.99 | 0.96 | 0.94–0.99 | |
High | 30 | 0.92 | 0.90–0.95 | 0.93 | 0.90–0.95 | |
Age | 70(median) | 1.0 | 1.0–1.0 | 1.02 | 1.01–1.02 | |
Gender | Men | 49 | 1 | Reference | 1 | Reference |
Women | 51 | 0.99 | 0.98–1.02 | 0.96 | 0.94–0.98 | |
Localization | Head | 68 | 1 | Reference | 1 | Reference |
Non-head | 19 | 1.3 | 1.2–1.3 | 1.1 | 1.07–1.13 | |
NOS/Overlapping lesion | 13 | 1.5 | 1.4–1.5 | 1.20 | 1.16–1.24 | |
Differentiation | Well | 3 | 1 | Reference | 1 | Reference |
Moderate | 11 | 1.1 | 1.1–1.2 | 1. | 1.13–1.30 | |
Poor | 11 | 1.7 | 1.6–1.8 | 1.5 | 1.43–1.64 | |
Undifferentiated | 1 | 2.9 | 2.5–3.4 | 1.95 | 1.69–2.25 | |
Unknown | 75 | 1.9 | 1.8–2.0 | 1.21 | 1.43–1.29 | |
Stage | local | 14 | 1 | Reference | 1 | Reference |
Beyond pancreas | 28 | 1.0 | 0.9–1.0 | 1203 | 1.15–1.24 | |
metastatic | 45 | 2.4 | 2.3–2.5 | 2.29 | 2.21–2.37 | |
unknown | 5 | 1.5 | 1.5–1.6 | 1.31 | 1.26–1.37 | |
Resection | No | 90 | 1 | Reference | 1 | Reference |
Yes | 10 | 0.3 | 0.3–0.3 | 0.43 | 0.41–0.45 | |
Adjuvant chemotherapy | No | 80 | 1 | Reference | Not included in multivariable analysis | |
Yes | 20 | 0.3 | 0.3–0.3 |
CI: Confidence Interval.