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. 2016 Nov 10;10(11):e0004983. doi: 10.1371/journal.pntd.0004983

Fig 4. Alignments among B. bovis, B. microti, T equi and functionally defined Plasmodium Ap2 domains.

Fig 4

Alignments of: (A) B. bovis BBOV_II005480, B. microti BBM_I03085, and T. equi BEWA_022490 with P. berghei PB000752.01.0, a domain involved in the development of sexual-stage forms in Plasmodium (AP2-G). (B) AP2 domain of the protein encoded by the B. bovis AP2 gene BBOV_I004280, B. microti BBM_II03250, and T. equi BEWA_041620 with putative orthologues in P. berghei (PB00572.01) and P. falciparum, (PF11_0442). Both Plasmodium AP2 proteins are required for the development of ookinetes, and known as AP2-O. (C) B. bovis BBOV_II001610, B. microti BBM_II02455, and T. equi BEWA_008880 with P. berghei PB000752.01.0, a domain involved in the development of sporozoites (AP2-Sp). Predicted secondary structures for the domains of interest are depicted at the top of each of the alignments.