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Survival curves for progression to advanced AMD (GA or CNV) and genotype at two associated variants in the CFH locus. Survival curves showing the predicted progression rate from intermediate (grade 3) to advanced (grade 4 or 5) AMD with respect to the number of risk alleles at (a) nominally significant CFH:rs10737680 (P = 0.02, unadjusted for multiple testing), and (b) the associated SNP CFH:rs6677604 (P = 0.02), for females 67 years of age.
