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. 2016 Nov 10;11(11):e0165983. doi: 10.1371/journal.pone.0165983

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© 2016 Ma et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Necroptosis signaling pathway includes RIPK1, RIPK3 and MLKL (B) Analysis of cpd 1% inhibition of 403 non-mutant kinases when tested at 1 μM concentration (the size of the red circle indicates a higher % inhibition). (C) Cpd 4 inhibits none of the 403 non-mutant kinases when tested at 1 μM concentration, but does inhibit pseudokinase MLKL.