Table 4. Meta-regression analysis with type of fertility treatment as independent variable to determine whether this independent variable could be of influence on the sensitivity and specificity of the sperm DNA fragmentation test.
| Sperm DNA fragmentation test | Sensitivity (95% CI) | p-value* | Specificity (95% CI) | p-value** | p-value*** | I2 |
|---|---|---|---|---|---|---|
| SCSA | 0.69 (0.60–0.77) | 0.00 | 0.33 (0.27–0.40) | 0.00 | 0.00 | 91 |
| SCD | - | - | - | - | - | - |
| TUNEL | 0.79 (0.64–0.89) | 0.52 | 0.33 (0.13–0.62) | 0.60 | 0.59 | 0 |
| Comet | 0.63 (0.46–0.78) | 0.08 | 0.60 (0.42–0.76) | 0.99 | 0.12 | 52 |
* meta-regression sensitivity
** meta-regression specificity
*** meta-regression joint model; het-erogeneity was quantified by using the I2 statistic