Table 3.

Comparison of the densities of histological features in chronic traumatic encephalopathy (CTE) cases with those in Alzheimer’s disease neuropathologic change (ADNC) not associated with CTE. Data are F ratios from two-factor repeated measures ANOVA

Feature	Case group	Brain region	Interaction	Post hoc
NFT	0.74 NS	5.32***	1.58 NS	NS
NT	1.82 NS	7.41***	2.02**	AD > CTE in STG, AM CTE > AD in CA2, CA4
DL	0.78 NS	10.05***	2.49**	CTE > AD in CA2, CA4, SFG
AT	5.26*	2.82***	1.07 NS	CTE > ADNC
GI	0.89 NS	0.92 NS	1.08 NS	NS
EN	0.04 NS	12.86***	1.44 NS	NS
N	3.26 NS	23.65***	1.41 NS	NS
V	1.54 NS	4.57*	0.70 NS	NS
NP	13.28**	3.83***	3.82***	AD > CTE especially in cortex

NFT, Neurofibrillary tangles; NT, Neuropil threads; DL, dot-like lesions; AI, Astrocytic inclusions; GI, Oligodendroglial inclusions; EN, abnormally enlarged neurons; N, Surviving neurons; V, vacuoles; NP, Neuritic plaques; NS, not significant; SFG, Superior frontal gyrus; AM, Amygdala.

^*P < 0.05;

^**P < 0.01;

^***P < 0.001.