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. 2016 Nov 11;3:51. doi: 10.3389/fmed.2016.00051

Table 1.

Patients with MF included in mutation analysis of TP53.

No. Gender/age (years) Clinical stage Mutation status of TP53 Disease duration at highest stage
1 Male/67 T3N3M1B0 Mutated: exon 4: c.100C > T (p.P34S); exon 4: c.254C > T (p.P85L); exon 4: c.430C > T (p.Q144stop) 7 years, DOD
2 Female/91 T3N0M0B0 Mutated: exon 8: c.811G > A (p.E271K); exon 5 and 6 unable to amplify 1 year, DOD
3 Female/67 T4N3M0B2 No mutations 10 years, DOD
4 Male/72 T3N2M0B0 No mutations 2 years, AWD
5 Female/89 T3N0M0B0 No mutations 8 years, DOC
6 Female/56 T4N1M0B1 No mutations 5 years, DOD
7 Male/69 T3N3M1B0 No mutations: exon 5 and 6 unable to amplify 3 years, DOD
8 Male/76 T4N3M0B1a No mutations 3 years, DOD
9 Female/65 T3N1M0B0 No mutations 14 years, AWD
10 Male/83 T3N0M0B0 No mutations 11 years, AWD
11 Female/55 T3N0M0B0 No mutations 5 years, AWD
12 Male/75 T3N0M0B0 No mutations in exon 7, 10: exon 4, 5, 6, 8, and 9 unable to amplify 3 years, DOC
13 Male/64 T4N3M0B2 Mutated: exon 5: c.449C > T (p.T150I) 4 years, DOD
14 Female/74 T3N0M0B0 No mutations 6 years, AWD
15 Female/71 T3N0M0B0 No mutations 12 years, AWD
16 Female/63 T3N3M0B0 No mutations: exon 4, 5, and 6 unable to amplify 5 years, DOC
17 Male/76 T3N0M1B0 Mutated: exon 5: c. 502C > T (p.H168Y); exon 5: c. 530C > A (p.P178H); exon 6: c. 670G > T (p.E224Stop) 3 years, DOD
18 Male/99 T3N0M0B0 Mutated: exon 8: c.818G > A (p.R273H) 2 years, DOC
19 Male/66 T3N2M0B0 Mutated: exon 5: c.457C > T (p.P153S); exon 5: c.461G > A (p.G154D) 5 years, DOD

AWD, alive with disease; DOD, dead of disease; DOC, dead of other causes.