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Effects of Zn2+ on K D and B max values of [3H]8-OH-DPAT obtained in saturation binding experiments in 5-HT1A receptors in HEK293 cells
| Zn2+ [μM] | 0 | 10 | 100 | 500 | 1000 | 2500 | 5000 |
| K D [nM] | 2.9 ± 0.1 | 5.0 ± 0.1 | 6.0 ± 0.4 | 6.9 ± 0.2 | 8.2 ± 0.9 | 8.6 ± 0.6 | 9.6 ± 0.6 |
| B max [pM/mg prot] | 4.5 ± 0.3 | 5.8 ± 0.7* | 6.2 ± 2.0 | 4.7 ± 0.7 | 4.0 ± 0.6 | 3.1 ± 1.2* | 2.5 ± 0.8* |
*p < 0.05
