Table 4.

Overview of relevant processes and mechanism involved in DILI of training compounds

Training compound	1	2	3	4	5
	Mitotoxicity	CRM	Lysosomal	Biliary	Immune
Fialuridine	✓
Acetaminophen	✓	✓			✓ (Innate)
Diclofenac	✓	✓		✓
Amiodarone	✓		✓
Perhexiline			✓	✓
Bosentan				✓
Tolcapone	✓	✓		✓
Nefazodone		✓		✓
Troglitazone	✓	✓	✓	✓
Ximelagatran					✓ (Adaptive)
Flucloxacillin					✓ (Adaptive)