Table 5.
Absolute volumes V100, V200 and V400 (mean ± st. dev.) of normal tissue receiving a dose of PD, 2 × PD and 4 × PD per fraction. Numbers 1, 2 and 3 represent manual, HIPO and IPSA optimization, respectively
| T/R | 1 | 2 | 3 | p (1-2) | p (1-3) | p (2-3) |
|---|---|---|---|---|---|---|
| V100 (cm3) | 31.4 ± 10.5 | 29.2 ± 10.9 | 35.4 ± 15.6 | 0.587 | 0.440 | 0.210 |
| V200 (cm3) | 3.9 ± 2.3 | 3.5 ± 2.1 | 3.8 ± 2.5 | 0.648 | 0.945 | 0.691 |
| V400 (cm3) | 0.5 ± 0.6 | 0.1 ± 0.6 | 0.4 ± 0.4 | 0.185 | 0.474 | 0.185 |
| T/R + N | 1 | 2 | 3 | p (1-2) | p (1-3) | p (2-3) |
| V100 (cm3) | 35.7 ± 9.3 | 28.8 ± 12.4 | 31.3 ± 9.2 | 0.036 | 0.024 | 0.343 |
| V200 (cm3) | 4.0 ± 1.7 | 2.7 ± 2.3 | 3.0 ± 1.8 | 0.115 | 0.091 | 0.544 |
| V400 (cm3) | 0.5 ± 0.4 | 0.6 ± 0.8 | 0.3 ± 0.3 | 0.599 | 0.095 | 0.225 |