Table 4. Proportions and odds ratio of anti-angiogenic diseases in relation to ONJ in the groups of patients not taking bisphosphonates.
| Anti-angiogenic disease | Group 2A (n=32) | Group 2B (n=44) | Odds ratio | P-value | ||
|---|---|---|---|---|---|---|
| Yes | No | Yes | No | |||
| DM | 6 (18.8) | 26 (81.2) | 6 (13.6) | 38 (86.4) | 1.46 | 0.548 |
| Hypertension | 19 (59.4) | 13 (40.6) | 18 (40.9) | 26 (59.1) | 2.11 | 0.114 |
| RA | 3 (9.4) | 29 (90.6) | 1 (2.3) | 43 (97.7) | 4.45 | 0.206 |
| Hyperlipidemia | 3 (9.4) | 29 (90.6) | 3 (6.8) | 41 (93.2) | 1.41 | 0.684 |
| More than 1 disease | 23 (71.9) | 9 (28.1) | 20 (45.5) | 24 (54.6) | 3.06 | 0.024 |
(ONJ: osteonecrosis of the jaw, DM: diabetes mellitus type II, RA: rheumatoid arthritis, More than 1 disease: existence of more than one of the antiangiogenic diseases above)
Group 2A: ONJ group, Group 2B: control group.