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Effect of the ribonucleotide backbone on the BER activity. The 5′-end 6-FAM-labeled DNA substrate containing rG, 8-oxo-rG, or 8-oxo-dG (200 nm) was incubated for 30 min at 37 °C in the absence (−) or presence (+) of OGG1 (100 nm) and APE1 (40 nm).
