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. 2016 Nov 11;6:36871. doi: 10.1038/srep36871

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) A stack of 55 images is collected (or 110 if the data from the two pump wavelengths is concatenated), with each image containing a different pump-probe time-delay (−1.5 to 4 ps). Inset shows the dynamics of four pixels in the composite stack. (b) Melanin dynamics (i.e., transient responses) measured from hundreds of thousands spatial pixels are process with a Beta Process Factor Analysis (BPFA) algorithm followed by Principal Component Analysis (PCA) to compute the Principal Components (PCs). (c) Projection of the data onto 3 PCs can be described in spherical coordinates. After normalization, points lay in the unit sphere which are then projected onto a tangent plane at a given point γ on the sphere, such that great circles (shortest paths) on a sphere correspond to straight lines in the new tangent plane with directions and .

Inline graphic — (a) A stack of 55 images is collected (or 110 if the data from the two pump wavelengths is concatenated), with each image containing a different pump-probe time-delay (−1.5 to 4 ps). Inset shows the dynamics of four pixels in the composite stack. (b) Melanin dynamics (i.e., transient responses) measured from hundreds of thousands spatial pixels are process with a Beta Process Factor Analysis (BPFA) algorithm followed by Principal Component Analysis (PCA) to compute the Principal Components (PCs). (c) Projection of the data onto 3 PCs can be described in spherical coordinates. After normalization, points lay in the unit sphere which are then projected onto a tangent plane at a given point γ on the sphere, such that great circles (shortest paths) on a sphere correspond to straight lines in the new tangent plane with directions and .