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. 2016 Nov 11;6:36829. doi: 10.1038/srep36829

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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REN MPM cells (1 × 10⁶ cells) were injected into the thoracic cavity of nude mice. After 10 days, mice were treated with PBS, control adenovirus or EPCR adenovirus as described in Fig. 4. At the end of 30 days following tumor cell implantation, mice were euthanized, and pleural lavages were collected. Cytokine levels in the pleural lavage were quantified using ELISA (a) TNFα; (b) IFNγ (n = 13 to 16 mice/group). *p < 0.05 in one-way ANOVA. Values in Ad.EPCR treated animals also differ in a statistically significant manner from PBS or Ad.Con treated animals.