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. 2016 Nov 11;6:36845. doi: 10.1038/srep36845

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Representative morphologies are shown at different time points during cell reprogramming on surfaces coated (a with or b) without vitronectin (VN). PS+VN is the positive control. White arrows indicate differentiated cells within hiPSC colonies, while black arrows indicate fully reprogrammed hiPSC colonies with a defined cell boundary.