Table 1. General characteristics of transwomen.
| Antropometry | Mean (SD) | p-value | |
|---|---|---|---|
| Baseline | 12 months follow-up | ||
| BMI (kg/m2) | 23.90 (4.34) | 24.28 (4.01) | 0.78 |
| Weight (kg) | 76.87 (15.45) | 78.50 (14.68) | 0.743 |
| WTH-Ratio | 0.89 (0.06) | 0.86 (0.078) | 0.11 |
| Total lean mass (kg) | 59.49 (10.65) | 56.45 (10.02) | 0.37 |
| Total fat (%) | 18.56 (4.46) | 23.92 (3.64) | <0.001 |
| Total lean mass (%) | 78.1 (4.17) | 72.71 (3.45) | <0.001 |
| Total fat mass (kg) | 14.65 (5.76) | 18.86 (5.36) | 0.026 |
| Grip-strength (kg) | 41.71 (7.77) | 41.88 (7.03) | 0.948 |
| Systolic blood pressure (mmHg) | 127.44 (22.65) | 123.06 (12.60) | 0.482 |
| Diastolic blood pressure (mmHg) | 76.94 (13.12) | 75.00 (8.83) | 0.609 |
| Life style | |||
| Overall physical activity | 8.17 (1.63) | 8.36 (1.88) | 0.736 |
| Current smoking | 0.16 (0.37) | 0.16 (0.37) | 1 |
| Alcohol intake/week (glasses) | 2.32 (2.93) | 1.95 (3.19) | 0.713 |
| Lab measurements | |||
| Hormones | |||
| Estradiol (pg/ml | 24.36 (7.11) | 64.75 (32.93) | <0.001 |
| Total testosterone (ng/dl) | 591.28 (162.67) | 57.65 (131.78) | <0.001 |
| Free testosterone (nmol/l) | 11.36 (3.46) | 1.24 (2.98) | <0.001 |
| FSH (μU/ml) | 5.50 (4.14) | 0.81 (1.44) | <0.001 |
| LH (μU/ml) | 5.58 (2.34) | 0.75 (1.63) | <0.001 |
| SHBG (nmol/l) | 39.07 (18.14) | 44.40 (21.93) | 0.425 |
| Leptin (μg/l) | 4.89 (4.14) | 11.41 (5.24) | <0.001 |
| Other | |||
| Hematocrit (%) | 45.21 (2.67) | 42.73 (1.79) | 0.002 |
| Total cholesterol (mg/dl) | 185.47 (37.43) | 166.26 (31.07) | 0.094 |
| HDL (mg/dl) | 53.95 (11.66) | 56.84 (8.50) | 0.039 |
| LDL (mg/dl) | 112.99 (34.16) | 103.10 (28.43) | 0.339 |
| Triglycerides (mg/dl) | 92.32 (52.66) | 81.21 (27.47) | 0.422 |
| Insulin (mIU/l) | 7.67 (3.47) | 12.84 (7.86) | 0.018 |
| Fasting glucose (mg/dl) | 87.63 (9.88) | 87.06 (13.97) | 0.886 |
| HOMA-Index | 1.59 (0.87) | 2.66 (1.85) | 0.04 |
BMI: body mass index; WTH: waist-to-hip; FSH: follicle-stimulating hormone; LH luteinizing hormone HOMA: Homeostasis Model Assessment; HDL: high-density lipoprotein cholesterol LDL: low-density lipoprotein cholesterol.