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. 2016 Nov 8;7:13316. doi: 10.1038/ncomms13316

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The patients involved in this study are distributed throughout China with the majority recruited from Shandong (n=389), Hunan (n=264) and Guangdong (n=202) provinces. The map was generated from a template downloaded from the public standard map service (http://219.238.166.215/mcp/index.asp) of the National Administration of Surveying, Mapping and Geoinformation of China (http://www.sbsm.gov.cn). The template is freely available for public download and use. Different colours represent different geographical regions, provinces or municipalities in China. The size of the red circles denotes the relative number of patients from each locale. Editor's Note: Nature Communications remains neutral with regard to jurisdictional claims in published maps.