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. 2016 Nov 10;17:466. doi: 10.1186/s12891-016-1310-6

Table 3.

Baseline frequencies of semi-quantitative MRI biomarkers – osteophytes

MRI feature Biomarker Overall n (%) Controls Cases p-value
Osteophytes Number of locations affected by any osteophyte
 0 19 (3 %) 15 (3.7 %) 4 (2.1 %)
 1 34 (6 %) 30 (7.4 %) 4 (2.1 %)
 2 42 (7 %) 36 (8.9 %) 6 (3.1 %)
 3 58 (10 %) 43 (10.6 %) 15 (7.7 %)
 4 54 (9 %) 39 (9.6 %) 15 (7.7 %)
 5 47 (8 %) 38 (9.4 %) 9 (4.6 %)
 6 45 (8 %) 28 (6.9 %) 17 (8.8 %)
 7 37 (6 %) 23 (5.7 %) 14 (7.2 %)
 8 49 (8 %) 26 (6.4 %) 23 (11.9 %)
 9 41 (7 %) 26 (6.4 %) 15 (7.7 %)
 10 47 (8 %) 30 (7.4 %) 17 (8.8 %)
 11 48 (8 %) 33 (8.1 %) 15 (7.7 %)
 12 79 (13 %) 39 (9.6 %) 40 (20.6 %)
Number of locations affected by any osteophyte category <0.001*
 0–2 95 (16 %) 81 (20.0 %) 14 (7.2 %)
 3–5 159 (27 %) 120 (29.6 %) 39 (20.1 %)
 6+ 346 (58 %) 205 (50.5 %) 141 (72.7 %)
Max osteophyte score in knee
 0 19 (3 %) 15 (3.7 %) 4 (2.1 %)
 1 290 (48 %) 209 (51.5 %) 81 (41.8 %)
 2 202 (34 %) 132 (32.5 %) 70 (36.1 %)
 3 89 (15 %) 50 (12.3 %) 39 (20.1 %)
Max osteophyte score in knee category 0.011*
 0–1 309 (52 %) 224 (55.2 %) 85 (43.8 %)
 2 202 (34 %) 132 (32.5 %) 70 (36.1 %)
 3 89 (15 %) 50 (12.3 %) 39 (20.1 %)

*statistically significant at p < 0.05; p values refer to differences between cases and controls across all grades