Table 9.
Twenty-four month change in semi-quantitative MRI biomarkers – meniscus
| MRI feature | Biomarker | Overall n (%) | Controls | Cases | p-value |
|---|---|---|---|---|---|
| Yes | 102 (17 %) | 59 (14.5 %) | 43 (22.2 %) | ||
| Meniscus | Meniscal Morphology: 24 Month Number of regions with worsening | ||||
| 0 | 505 (84 %) | 365 (90.1 %) | 140 (72.2 %) | ||
| 1 | 67 (11 %) | 31 (7.7 %) | 36 (18.6 %) | ||
| 2 | 25 (4 %) | 7 (1.7 %) | 18 (9.3 %) | ||
| 3 | 1 (0 %) | 1 (0.2 %) | 0 (0.0 %) | ||
| 5 | 1 (0 %) | 1 (0.2 %) | 0 (0.0 %) | ||
| Meniscal Morphology: 24 Month Any regions with worsening | <0.001 | ||||
| No | 505 (84 %) | 365 (90.1 %) | 140 (72.2 %) | ||
| Yes | 94 (16 %) | 40 (9.9 %) | 54 (27.8 %) | ||
| Meniscal Extrusion Medial - 24 Month worsening | <0.001 | ||||
| No | 512 (86 %) | 369 (91.3 %) | 143 (74.1 %) | ||
| Yes | 85 (14 %) | 35 (8.7 %) | 50 (25.9 %) | ||
| Meniscal Extrusion Lateral - 24 Month worsening | |||||
| No | 599 (100 %) | 405 (99.8 %) | 194 (100.0 %) | ||
| Yes | 1 (0 %) | 1 (0.2 %) | 0 (0.0 %) |
*statistically significant at p < 0.05; p values refer to differences between cases and controls across all grades