Table 2.
Association of fat depots and markers of adipose tissue dysfunction with impaired fasting glucose and newly diagnosed type 2 diabetes mellitus
| Abnormalities | Normoglycemic | Impaired fasting glucose | Newly diagnosed type 2 diabetes mellitus |
|---|---|---|---|
| Odd ratio (95% I.C) | Odd ratio (95% I.C) | Odd ratio (95% I.C) | |
| Model 1 | Reference values | ||
| Fatty liver | 1 | 3.36 (2.43–4.65) | 5.68 (3.01–10.69) |
| Elevated VAT | 1 | 2.79 (1.91–4.05) | 2.84 (1.38–5.82) |
| Adipo-IR | 1 | 3.80 (2.65–5.47) | 2.15 (1.54–3.02) |
| Low adiponectin | 1 | 1.84 (1.22–2.77) | 3.29 (1.64–6.58) |
| Elevated FFA | 1 | 1.37 (0.97–1.94) | 1.62 (0.87–3.01) |
| Model 2 | |||
| Fatty livera | 1 | 2.46 (1.73–3.49) | 4.26 (2.18–8.25) |
| Elevated VATb | 1 | 1.37 (0.89–2.11) | 1.09 (0.49–2.44) |
| Adipo-IR | 1 | 2.69 (1.82–3.96) | 2.15 (1.06–4.37) |
| Low adiponectin | 1 | 1.46 (0.96-2.22) | 2.54 (1.26–5.12) |
| Elevated FFA | 1 | 1.29 (0.91-1.85) | 1.51 (0.80–2.85) |
Model 1 adjusted for age and gender
Model 2 adjusted for age, gender, body mass index, high density lipoprotein cholesterol and triglycerides
VAT visceral abdominal tissue, Adipo-IR adipose tissue insulin resistance, FFA free fatty acids
aAdditional adjustment for elevated VAT
bAdditional adjustment for fatty liver