Table 2.
# | Age | Sex | Histology of primary tumor | Tumor size (cm) | Encapsulation | Capsular invasion | Vascular invasion | Margin status | Highest grade carcinoma of LN metastasis | ETE | DM |
---|---|---|---|---|---|---|---|---|---|---|---|
1a | 44 | M | Hürthle cell carcinoma | 7.2 | Complete | Extensive | Extensive | Negative | PTC, classical | Microscopic | During FU |
2 | 75 | F | Hürthle cell carcinoma | 5.0 | Complete | Extensive | Extensive | Negative | NA | None | During FU |
3 | 44 | M | Hürthle cell carcinoma | 4.0 | Complete | Focal | Extensive | Negative | NA | None | During FU |
4 | 70 | M | Hürthle cell carcinoma | 5.5 | Complete | Focal | None | Negative | NA | None | At presentation |
5 | 66 | M | FVPTC | 5.0 | Complete | Extensive | Extensive | Negative | NA | None | At presentation |
6 | 28 | F | FVPTC | 2.0 | None | NA | None | Positive | FVPTC | Microscopic | At presentation |
7 | 78 | F | PTC, classical | NA | None | NA | None | Positive | NA | GET | At presentation |
8 | 76 | M | PTC, classical | 2.0 | Partial | NA | Focal | Negative | PTC solid | Microscopic | At presentation |
9 | 58 | M | PMC | 0.4 | None | NA | Focal | Negative | PDTC | None | During FU |
10 | 51 | F | PMC | 0.4 | None | NA | None | Negative | PDTC | None | At presentation |
11 | 77 | M | PMC | 0.8 | Partial | NA | None | Negative | PDTC | GET | During FU |
This patient harbored multifocal thyroid carcinomas, including an encapsulated thyroid-confined 7.2 cm Hürthle cell carcinoma with extensive vascular and capsular invasion, an encapsulated Hürthle cell carcinoma with two foci of capsular invasion, and two PTC (one of which had microscopic extrathyroidal extension into the perithyroidal adipose tissue). The histological classification of the lymph node metastases was papillary carcinoma, classical variant.
LN, lymph node; M, male; F, female; FVPTC, follicular variant papillary thyroid carcinoma; PMC, papillary microcarcinoma; PDTC, poorly differentiated carcinoma according to MSKCC criteria; NA, not applicable; FU, follow-up; DM, distant metastasis.