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. 2016 Nov 1;26(11):1588–1597. doi: 10.1089/thy.2016.0247

Table 2.

Clinicopathologic Characteristics of the 11 Patients Harboring Non-Poorly Differentiated, Non-Tall-Cell Variant Thyroid Carcinomas

# Age Sex Histology of primary tumor Tumor size (cm) Encapsulation Capsular invasion Vascular invasion Margin status Highest grade carcinoma of LN metastasis ETE DM
1a 44 M Hürthle cell carcinoma 7.2 Complete Extensive Extensive Negative PTC, classical Microscopic During FU
2 75 F Hürthle cell carcinoma 5.0 Complete Extensive Extensive Negative NA None During FU
3 44 M Hürthle cell carcinoma 4.0 Complete Focal Extensive Negative NA None During FU
4 70 M Hürthle cell carcinoma 5.5 Complete Focal None Negative NA None At presentation
5 66 M FVPTC 5.0 Complete Extensive Extensive Negative NA None At presentation
6 28 F FVPTC 2.0 None NA None Positive FVPTC Microscopic At presentation
7 78 F PTC, classical NA None NA None Positive NA GET At presentation
8 76 M PTC, classical 2.0 Partial NA Focal Negative PTC solid Microscopic At presentation
9 58 M PMC 0.4 None NA Focal Negative PDTC None During FU
10 51 F PMC 0.4 None NA None Negative PDTC None At presentation
11 77 M PMC 0.8 Partial NA None Negative PDTC GET During FU
a

This patient harbored multifocal thyroid carcinomas, including an encapsulated thyroid-confined 7.2 cm Hürthle cell carcinoma with extensive vascular and capsular invasion, an encapsulated Hürthle cell carcinoma with two foci of capsular invasion, and two PTC (one of which had microscopic extrathyroidal extension into the perithyroidal adipose tissue). The histological classification of the lymph node metastases was papillary carcinoma, classical variant.

LN, lymph node; M, male; F, female; FVPTC, follicular variant papillary thyroid carcinoma; PMC, papillary microcarcinoma; PDTC, poorly differentiated carcinoma according to MSKCC criteria; NA, not applicable; FU, follow-up; DM, distant metastasis.