Table 1.
Outcome measures in subgroups/mice # (subgroups, randomly selected) | Sham | Mild SCI | Moderate SCI | Severe SCI |
---|---|---|---|---|
BMS | 15 | 15 | 15 | 14 |
OP/NOR/Y-maze | 15 | 15 | 15 | 13 |
TS/FS | 15 | 15 | 15 | 12 |
SP/SDPA | 15 | 15 | 13 | 11 |
IHC for BrdU/DCX/NeuN | 8 | 9 | 9 | 9 |
IHC for BrdU/Iba-1/GFAP | 6 | 5 | 5 | 5 |
IHC for GRP78/DCX | 6 | 7 | 6 | 6 |
IHC for CCL21/NeuN | 5 | 6 | 5 | 6 |
NeuN stereology | 5 | 5 | 6 | 5 |
Iba-1 stereology | 5 | 6 | 6 | 6 |
SCI, spinal cord injury; BMS, Basso Mouse Scale; OP, open field; NOR, novel object recognition; TS, tail suspension; FS, forced swim; SP, sucrose preference; SDPA, step-down passive avoidance; BrdU, bromodeoxyuridine; DCX, doublecortin; NeuN, neuronal nuclei; IHC, immunohistochemistry; Iba-1, ionized calcium binding adaptor molecule 1; GFAP, glial fibrillary acidic protein; GRP78, glucose-regulated protein 78; CCL21, chemokine (C-C motif) ligand 21.