FIG 1.
Schematic diagrams of the genome structure of wild-type HSV-1(F) and the relevant domains of the recombinant viruses used in this study. (A) Line 1, wild-type HSV-1(F) genome (UL and Us, unique long and unique short domains, respectively); line 2, domains of the Us5 to Us7 genes; line 3, domain of the Us6 (gD) gene; lines 4 to 7, recombinant viruses with mutations in the gD gene. (B) Amino acid sequence of the cytoplasmic domain of gD. The arginine cluster discussed in this paper is underlined.