FIG 4.

Multiple epitopes elicited by vaccination in human volunteers revealed by use of a peptide microarray. Purified hMAbs were tested on JPT Peptide Technologies slides containing overlapping peptides for a diverse set of gp120s from multiple clades (identified on the right), including consensus sequences. (A) Peptide microarray against multiple gp120 protein peptides, focused on epitopes in clades C2, C5, and V3. The numbers on the x axes of panel A are amino acid positions. (B) ELISA against a consensus clade B V3 circular peptide.