Table 4.

The effects of actin-perturbing agents on hemoglobin localization to the FV

	% FV with hemoglobin	Odds ratio	95% confidence interval	P-value
E-64	94	Referent	–	–
CD	96	0.77	(0.50, 1.18)	0.231
JAS	20	0.02	(0.01, 0.04)	<0.001
CD versus JAS	–	33.53	(18.91, 59.46)	<0.001

A modeled logistic regression with linear contrasts to compare treatment groups (JAS to untreated, CD to untreated, CD to JAS) of the incidence of swollen FV filled with electron-dense undigested hemoglobin. Significance was determined when P≤0.05. PE were counted from at least two separate experiments per treatment group (n=300). CD, cytochalasin D; FV, food vacuole; JAS, jasplakinolide. n, number of PE analyzed.