Table 2. Summary of peroxisome size and import defects in fatty acid β-oxidation mutants.
Mutant | Defect | Peroxisome size | PTS2 processing | PTS1 import |
---|---|---|---|---|
pxa1 | Fatty acid import into peroxisomes | Wta | Wtb | Wtb |
lacs6-1 lacs7-1 | Fatty acid import and activation | Wtc | Not determined | Not determined |
acx1-2 acx2-1 | Fatty acid β-oxidation | Larged | Not determined | Not determined |
mfp2 | Fatty acid β-oxidation | Largee | Defectb | Defectb |
ped1 | Fatty acid β-oxidation | Largef | Defectg | Defectg |
pxn | NAD+ and CoA import into peroxisomes | Largeh | Wtb | Wtb |
pxa1 pxn | Fatty acid, NAD+, and CoA import into peroxisomes | Wtb | Wtb | Wtb |
pxn ped1 | NAD+ and CoA import into peroxisomes and fatty acid β-oxidation | Largeb | Enhanced defectb | Enhanced defectb |
This work and Hayashi et al. (2002).
This work.
This work and Rylott et al. (2006).
This work and Hayashi et al. (1998).
This work and Burkhart et al. (2013).
This work and Mano et al. (2011).