Figure 4.
PIP calibration with 100 initial loci (∼65 causal loci). The top two panels show results from CAVIARBF_ENET_CV, bottom two panels are from PAINTOR_top5t. Left two panels, 5 informative annotations with effect size log5; right two panels, 40 informative annotations with effect size log1.5. The x-axis shows the center of 20 bins of width 0.05. The y-axis is the proportion of causal SNPs. The blue points show the proportion of causal SNPs in each bin. The red bars show the 95% C.I. (Wilson inversion of score statistic) of the proportion assuming a binomial distribution in each bin. 100 data sets were used in each panel.