Table 7. Body mass index (BMI) and risk of incident tuberculosis (TB) disease among household contacts over 19 years of age.
All secondary TB cases | Microbiologically confirmed secondary pulmonary TB cases | |||
---|---|---|---|---|
Multivariate HRa (95% CI) N = 6487 | p value | Multivariate HRa (95% CI) N = 6457 | p value | |
BMI 18.5 to < 25 kg/m2 | Reference | Reference | ||
BMI 25 to < 30 kg/m2 | 0.45 (0.32–0.63) | <0.001 | 0.46 (0.32–0.67) | <0.001 |
BMI 30 to < 35kg/m2 | 0.37 (0.22–0.63) | <0.001 | 0.40 (0.23–0.71) | 0.002 |
BMI ≥ 35 kg/m2 | 0.30 (0.12–0.74) | 0.009 | 0.37 (0.15–0.92) | 0.03 |
p trend <0.001 | p trend <0.001 |
HR, Hazard Ratio.
a Adjusted for age, sex, BMI categories, comorbid disease (heart disease, high blood pressure, asthma, kidney disease, use of steroids or chemotherapy or immunosuppressant, any other self-reported chronic illness), BCG scar, isoniazid preventive therapy, heavy alcohol consumption, tobacco use, HIV status, socioeconomic status, self-reported DM, TB history, index smear status, and index cavitary disease.