Table 3. Shared molecular bases of T2D, BD, and CAD as revealed by NetPocos.

Gene Name	Frequency	T2D	BD	CAD
CAD
WWOX	102	NO	YES	YES
CSMD1	80	NO	YES	NO
APP	77	NO	NO	NO
PARK2	74	YES	YES	NO
GRID1	64	YES	YES	NO
DOCK10	61	YES	NO	NO
CUL3	56	NO	NO	NO
DENND1A	56	NO	NO	NO
CD36	52	NO	YES	YES
CNTNAP2	49	NO	YES	NO
T2D
CSMD1	38	NO	YES	NO
A2BP1	35	NO	YES	NO
FHIT	35	NO	NO	NO
CNTNAP2	34	NO	YES	NO
PTPRD	32	YES	YES	NO
CACNA2D3	31	NO	NO	NO
WWOX	29	NO	YES	YES
NRG1	28	YES	YES	YES
SUPT3H	28	YES	NO	NO
CDH13	26	NO	YES	YES
BD
PARK2	54	YES	YES	NO
NRG1	48	YES	YES	YES
ADRB2	47	YES	YES	YES
WWOX	43	NO	YES	YES
APP	41	NO	NO	NO
CACNA2D3	40	NO	NO	NO
CUL3	40	NO	NO	NO
KIF16B	40	NO	NO	NO
SNX29	35	NO	NO	NO
DAPK1	33	NO	NO	NO

For each disease, ten most frequent genes that are involved in NetPocos selected by L1 regularized logistic regression in risk prediction are listed. Previously reported association of these genes with the three diseases are indicated with a “Yes” or “No” in the respective column of each row.