Table 1. Properties of PLGA NPs constructs used in this study.
| Formulation | Hydrodynamic diameter (nm) | Zeta Potential (mV) | Polydispersity Index | Mobility (umcm/Vs) | Conductivity (mS/cm) | OVA EE (%)d | MPLA EE (%) |
|---|---|---|---|---|---|---|---|
| PLGAa | 431 ± 162 | -14.8 | 0.141 | -1.159 | 18 | - | - |
| PLGA/OVAb | 658.1 ± 273.7 | -11.3 | 0.518 | -0.885 | 19 | 100 ± 0.5 | - |
| PLGA/MPLAc | 400 ± 125 | -8.58 | 0.947 | -0.672 | 18 | - | 98.41 ± 0.09 |
| PLGA/OVA/MPLA | 566.7 ± 339.3 | -9.41 | 0.358 | -0.737 | 18 | 90.8 ± 0.1 | 97.34 ± 0.01 |
a PLGA = poly (lactic-co-glycolic acid)
b OVA = ovalbumin
c MPLA = monophosphoryl Lipid A
d EE = encapsulation efficiency