Table 3. Protein expression in DAD subgroups and control group.

	Sepsis	H1N1	Lepto	control	p
AQP1 (μm2/ μm)	0.41 [0.39]	0.60 [0.39]	0.57 [0.41]	0.73 [0.48]	NS
AQP3 (μm2/ μm)	1.06 ± 0.41	0.7 ± 0.38	0.85 ± 0.5	0.61 ± 0.22	0.011*
AQP5 (μm2/ μm)	0.81 [0.46]	0.42 [0.47]	0.18 [0.92]	0.13 [0.12]	0.001*
Na-K-ATPase (μm2/ μm)	1.73 [1.04]	1.58 [1.1]	0.48 [2]	0.69 [0.65]	0.004*
ENaC (μm2/ μm)	0.53 [0.24]	0.46 [0.58]	0.62 [0.55]	0.83 [0.61]	0.002**

Data are expressed as median [IQR] or mean ± (SD). DAD: Diffuse alveolar Damage, AQP: Aquaporin, ENaC: Epithelial Na⁺ Channel; Lepto: leptospirosis, NS: non-significant.

*, sepsis > control;

**, H1N1 < control.

There was no significant difference in protein expression when only the subgroups of DAD with different etiologies were compared.