Table 1. Characteristics of the patients with malaria included in the study.
| Spain | Mozambique | ||||
|---|---|---|---|---|---|
| Patient characteristics | Travelers (n = 21) | SM (n = 43) | UM (n = 43) | Adults (n = 25) | P |
| Age (years), median (IQR) | 34 (29–40) | 2.4 (1.3–3.6) | 2.6 (1.3–3.6) | 36 (30–46) | 0.791 |
| qPCR Parasite density*, median(IQR) | 724(322–9973) | 9060(2290–31982) | 3618(1050–13623) | 10260(2267–38327) | 0.022 |
| MOI, median (IQR) | 2 (1–3) | 3 (3–5) | 3 (2–4) | 2 (2–3) | 0.106 |
| Males, n (%) | 16 (76) | 28 (65) | 28 (65) | 16 (64) | 1.000 |
| Clinical manifestation of SM a (n) | |||||
| Cerebral malaria | - | 3 | - | - | |
| Severe anaemia | - | 13 | - | - | |
| Multiple seizures | - | 11 | - | - | |
| Prostration | - | 34 | - | - | |
| Hypoglicemia | - | 2 | - | - | |
| Acidosis/Respiratory Distress | - | 17 | - | - | |
IQR, Interquartile range; SM, severe malaria; UM, uncomplicated malaria; MOI, multiplicity of infection.
*, Expressed as parasites per μL.
a, Nineteen (44%) out of the 43 SM cases had a single criterion of malaria severity and the rest overlapping symptoms (13 [30%] had two and 11 [26%] three or more).